The Effect Of Giving Cloves Extract (Syzygium Aromaticum) On Hair Growth And Histopathological Picture Of Skin Tissue In The Healing Process Of Dermapene Wounds In Wistar Strain White Rats

Abstract

Hair loss is a widespread concern and affects skin quality. Hair loss can occur due to
many factors. Based on previous research, clove plants can overcome hair loss problems.
This is because cloves can be used as extracts and contain secondary metabolites in the
form of flavonoids, saponins, tannins, and steroids.
This study is a true experimental study, using a post-test only control group design. The
sample in this study was 24 animals.
The results of the study concluded that administration of clove extract cream (Syzygium
aromaticum) affected hair growth. Based on the difference in average hair length in the
groups after testing. The conclusion of the research results stated that the greatest hair
growth was in test group 3 which was given clove extract with a concentration of 12%.
The group with the least hair growth was in the control group which was only given base
cream. Administration of clove extract cream (Syzygium aromaticum) in the group after
testing with concentrations of 3%, 9%, and 12% extra affected the healing process of
dermapen wounds in white rats (Rattus norvegicus) Wistar strain. Based on
phytochemical tests, it was shown that clove extract (Syzygium aromaticum) contains
secondary metabolites in the form of flavonoids, saponins, tannins, and steroids. These
compounds, especially flavonoids, help heal dermapen wounds and stimulate hair
growth.