Antioxidant And Anti Aging Activity Test Of Cloves (Syzygium Aromaticum)

Abstract

This study aimed to investigate the anti-aging effects of clove extract on collagen density
and its antioxidant activity in mice exposed to UVB light..
This study is a True experimental study, with the selection of the type of research design
used being Post Test Control Group Design, I used a control group and a treatment group
given clove extract after UVB exposure.
The total number of test animal samples in this study was 24. Test animals were grouped
randomly into 4 test groups, and 6 animals in each group.
This study concluded that the results of phytochemical analysis showed that clove extract
contains flavonoids, saponins, alkaloids, steroids, and tannins, with flavonoids as the key
to increasing collagen density. The antioxidant activity of clove extract is intense, with
an IC50 value of 17.62 ppm, included in the category of powerful antioxidants. Based on
the significance test using One-Way ANOVA, it is known that the control and treatment
groups have significant differences in collagen density. The treatment group has a denser
collagen density than the control group, and the results of histopathological observations
show that the control group produces collagen growth that is included in the thin category.
In contrast, the treatment group that was smeared with clove extract is included in the
dense category. These results indicate that clove extract, with its high antioxidant
capacity, can be a potential anti-aging agent by increasing collagen density.