Antioxidant and Anti-Aging Activity Test Pagoda Flower (Clerodendrum Paniculatum L)

Abstract

This study was conducted to test the antioxidant and anti-aging activity of pagoda flowers (Clerodendrum paniculatum L.). Antioxidant testing of pagoda flower extract through DPPH testing. Seeing the anti-aging activity of pagoda flower extract through differences in collagen density between the Control group without extract and treatment group 1 with 10% pagoda flower cream extract concentration, treatment 2 with 15% concentration, and treatment with 20% concentration of pagoda flower extract cream through DPPH testing obtained an IC50 value of 53.65 indicating strong antioxidant results. For the anti-aging activity of pagoda flower extract, the best collagen density area is group P3 and P2 because the collagen density is already very large and dense in the histopathological picture of skin tissue. The normality test uses Kolmogorov Smirnov with normally distributed data results p> 0.05. Then the homogeneity results using Levene's Test: the p-value is 0.675. So, the conclusion is that there is a significant difference in the average (mean) percentage of collagen density from the four groups.