Antioxidant And Anti Aging Activity Test Of Cloves (Syzygium Aromaticum)

Abstract

This study aimed to investigate the anti-aging effects of clove extract on collagen density and its antioxidant activity in mice exposed to UVB light..

This study is a True experimental study, with the selection of the type of research design used being Post Test Control Group Design, i used, with a control group and a treatment group given clove extract after UVB exposure.

The total number of test animal samples in this study was 24. The grouping of test animals was done randomly into 4 test groups and 6 animals in each group.

The results of this study concluded that the results of phytochemical analysis showed that clove extract contains flavonoids, saponins, alkaloids, steroids, and tannins, with flavonoids as the key to increasing collagen density. The antioxidant activity of clove extract is strong, with an IC50 value of 17.62 ppm included in the category of very strong antioxidants. Based on the significance test using One-Way ANOVA, it is known that the control group and the treatment group have significant differences in collagen density. The treatment group has a denser collagen density than the control group and the results of histopathological observations show that the control group produces collagen growth that is included in the thin category while the treatment group that was smeared with clove extract is included in the dense category. These results indicate that clove extract, with its high antioxidant capacity, can be a potential anti-aging agent by increasing collagen density.