The Jurnal Prima Medika Sains (JPMS) presents various results of field or laboratory research and literature studies in the fields of health and medicine. In this edition, there are 15 articles sourced from field research and laboratory research, 5 case report articles, and 3 article sourced from literature studies. We are committed to contributing to the development of science in the field of health. We sincerely hope that readers will be willing to contribute their writings so that this scientific communication medium can always exist and be sustainable. Finally, we express our gratitude to the authors who have contributed their writings and thoughts and do not forget to all those who have helped the publishing process so that it can be read by all readers.